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Maintaining consistency and quality during scale-up is one of the most challenging aspects of nano-TiO2 production. The factory must adhere to stringent quality control measures, using advanced analytical techniques like X-ray diffraction (XRD) and transmission electron microscopy (TEM) to ensure the purity and uniformity of the nanoparticles. Additionally, environmental safety and health considerations are paramount, given the potential risks associated with nanomaterials.

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Application:
1. Due to its rheological and optical properties, Lithopone offers technical and economic advantages wherever organic and inorganic resin systems need to be relatively highly pigmented for specific applications. Lithopone has therefore traditionally been used in putties, mastics, jointing and sealing compounds, primers, undercoats and marking paints. In powder coatings it is possible to replace TiO2 partially, very economically.

2. The low Mohs' hardness of Lithopone leads to low abrasiveness in comparison with TiO2.

3. Lithopone 30 % (= 30% zinc sulfide share) is proven to be of particular use as a TiO2 Substitute in thermoplastic masterbatches. Even at very high pigment loadings it disperses easily. A masterbatch containing 50 % TiO2 and 25 % Lithopone 30 % DS has the same hiding power as one containing 60 %TiO2. Cost savings are strongly related to the price ratio of Lithopone and TiO2 and the price of for example polyethylene or polypropylene.

4. The Lithopone batch has a much higher extrusion rate too. Furthermore the impact strength of many thermoplastics such as PP and ABS can be noticeably improved by using Lithopone as a TiO2 substitute. Generally spoken, Lithopone can be used at loadings up to 80 % by weight without causing polymer breakdown

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